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Histopathology report for Fizz. Vets opinion post 43

Thats really scary:shock:

Could you possibly get Wish and Badger injected with a smaller dose so theres still a little protection or is that not possible, I'm not really "up to date" with things like this:? :(
 
My dad just called. He reckons that its more likely the vets down there stuffed up and won't admit it, than it genuinely being VHD.

He also said we shouldn't vaccinate Badger because we are so sure it will kill him.

I need to go and do some litter trays.
 
Ok, take a deep breath and make yourself a cup of sugary tea before you do anything. You're in a panic and upset and noone can think clearly whilst in that state.
So the plan of action is
1) Clean out all litter trays
2) Remove the 3 buns from the possibly infected hutch
3) Loads of research on VHD

Personally if Badger were mine I wouldnt vaccinate him based just on the info you have so far. It could well be a colossal mix up at the lab. I would be surprised if VHD was present and your other buns are so far ok, as I would have thought they would be ill by now.
However this new strain throws abit of a spoke in the wheels :?
Maybe its worth calling the Bristol Rabbit Hospital for more info and opinions from specialists?
Xxxxx
 
This is really scary, but I'm just wondering if Fizz could have been a carrier and therefore showed positive when tested although he is not infectious.
I think very young rabbits are unaffected by VHD, but do they become carriers after that. Certainly with viruses in general they can lie dormant for many years and the carriers does not shed the virus at all times. I don't know enough about VHD and carriers but if that is so he may have proved positive whilst not actually suffering for it. Maybe someone with more technical and medical knowlegde could comment on it being possible.
 
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I've just had a call from my vet. We talked it all over, and he feels there is a large question mark over it actually being VHD. He feels there would be more evidence to suggest that by now, because in terms of VHD, 5 weeks is a long time.

He does feel we should vaccinate Wish, but not Badger, and a deep clean of the hutch is not going to go a miss.

He doesn't think they would be able to get Anivac or Lapinject in time, however, he did say they are intending to move over to Anivac within the next month (which is too late for these, but awesome news in general).

His advice was to not panic, just be aware and once he has had a look at the report he will know more, but for now, a big question mark.
 
Sky-O said:
I've just had a call from my vet. We talked it all over, and he feels there is a large question mark over it actually being VHD. He feels there would be more evidence to suggest that by now, because in terms of VHD, 5 weeks is a long time.

He does feel we should vaccinate Wish, but not Badger, and a deep clean of the hutch is not going to go a miss.

He doesn't think they would be able to get Anivac or Lapinject in time, however, he did say they are intending to move over to Anivac within the next month (which is too late for these, but awesome news in general).

His advice was to not panic, just be aware and once he has had a look at the report he will know more, but for now, a big question mark.
Click to expand...

Thats at least a form of good news, in a way, i guess, sort of.

Do you think it'd be possible for your vet to vet some lapinject from another surgery at all, knowing the issues with Cylap and also Wish's history/issues, to minimise the issues it could pose to her?

Just throwing ideas out there.
 
Er. If this is VHD and the French variation, are they going to want to 'destroy' all my bunnies?
 
I am really sorry you are going through this:cry: I am not up on the whole history with Fizz.

Could it be possible that Fizz had an underlying illness before he had the vaccine and therefore his body could not process the vaccine in the usual way?

I hope you can find the answer.
 
Kittykat23uk said:
I very much doubt it, its not even a notifiable disease anymore is it? When did Fizz pass away?
Click to expand...

No, its not for the UK strain, didn't know whether it would be different because its a new strain that they don't have a vaccination for (like when that turkey farm got that illness and all were destroyed).

It was 10th January. VHD stays in the environment for many months though.
 
hunny im so sorry for you:(

BUT our dazy-mae had a necropsy done and it said most likely vhd apart from no bleeding:?

bertie hadnt had his booster...neither dazy-mae or her sister had been vaccd...i was going to give them a week to recover from the journey here and stress issues with it. But then dazy mae became ill.....and had to be pts....

its odd indeed..i do wonder if theres a mutant variation of all diseases...humans as well as other pets and bunnies....

my mum had whooping cough as a kid..when she was 42 i got whooping cough and so did she..at the same time!! we were in africa at the time with my dad working and training folks. so i truly belive..different country..different strain.

HUGS xx
 
I have nothing useful to add theory wise but wish you well. I feel scared about my bunnies being not totally protected and I'm along way from the coast and the most immediate danger.

Thinking of you and hope to god it was nothing contagous that killed Fizz. Maybe work on the likely theory that if it had been VHD you would have known about it before now.
 
Sky-O said:
I don't know enough. I'm going to ask my vet to call the other vet and see what they say RE antibodies and such. I think he said it was to do with the coagulation of the blood or something that they thought it was VHD.

Likely he brought it with him when he came though, because he was here less than 24 hours before falling ill, and the incubation is 24-48 hours.

As far as I know, it doesn't and can't lie doormant though.

I need to get those three rabbits out of the accommodation and do a deep clean on it.

God I'm so stupid. Why did I not quarantine him properly.
Click to expand...

You weren't to know! What the vet said about clotting, that would seem to be consistent with VHD yes. Having done a little research, it seems VHD doesn't always cause the bun to bleed out, there can be just clotting which can cause internal organs to fail, by e.g. blocking the heart and this could happen before more extensive signs are evident (like liver damage etc). This is true for the existing strains not just a new one.

I think all you can really do is wait for more information, clean down as much as possible and hope that it was an isolated event if it definitely does urn out to be VHD.:?

Another thought, if it was VHD and he died shortly after arriving at yours, then he most likely had it already and as he died without presenting any symptoms, chances are good that it is not in their environment anymore. Especially if it was over 5 weeks ago! Fingers crossed!!!
 
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just read about the pm,I know I do not know very much compared to most others on here but it seems most likelt to be a big mistake surely?
Know that you must be having an awful time wondering what to do for the best.
Also we we hoping that somehow it would bring some more understanding on Flare-Hazel's unexpected death.
Sending big hugs to you and your rabbits this evening.:cry:
 
Here goes.. I obviously don't understand the language, but will translate it later and also

Diagnosis: Possibly Viral Haemorrhagic Disease in Rabbits

Histopathlogy Report.
Sections from necropsy smapples of various tissues from a 9-month-old, neutered male, domestic rabbit were exained microscopically.

LIVER: 1 sample received; 1 section examined
The sinusoids and vasculature generally are markedly hyperaemic, which is probably, at least in part, a result of terminal hypostatic congestion, but there are also many, apparently randomly scattered, minute foci oh hepatocytic necrosis, mostly confined to just one or two hepatocytes and most with a few accompanying inflammatory cells. There is no parenchymal haemorrhage in this section.

KIDNEY: 1 sample received; 1 section examined
The tissue in this section is al well preserved, i.e. there is no evidence of the cortical necrosis reportedly seen at necropsy. the only finding of ay note here is variable congestion of the glomerular capillaries, but no convincing microthrombi are seen. There is no tubuluar degeneration and no interstitial inflammation or fibross in this section.

SPLEEN: 1 sample received; 1 section examined
The section includes a portion of pancreas which as also examined. Apart from early autolytic change, these are histologically unremarkable.

LUNG: 1 sample received; 1 section examined
Microscopy reveals moderately severe congestion and widespread alveolar flooding, but with minimal accompanying cellular inflammation. Bronchial epithelia are moderately disintegrated (probably early autolysis) but there is little bronchus-associated lymphoid tissue (BALT).

HEART: 1 sample received; 1 section examined
This is histologically normal in appearance.



Diagnosis: Uncertain, but probably viral haemorrhagc disease.


Discussion: Histological diagnosis of Viral Haemorrhagic Disease of rabbits depends upon the presence of characteristic findings in various organs, none of which, alone, are considered pathognomonic. There include multifocal hepatocytic necrosis with or without haeorrhage; renal glomerular microthrombi, sometimes with tubulonephropathy; pulmonary congestion, alveolar floodig and haemorrhage; tracheal submucosal cogestion and haemorrhage- the more of these findings are present the greater the likelihood of VHD.

Despite the lack of convincing glomerular microthrombi in the kidney in thid case, the sever congeston and alveolar flooding in the lungs, in the abscence of appreciable inflammation, coupled with multifocal hepatocytic necrosis suggests that VHD was the likely cause of death.
 
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