Jack's-Jane
Wise Old Thumper
I have bought a trial Vetstream membership. On looking at information about pharmacology and therapeutics I came across details for Paracetamol.
Paracetamol
Anna Meredith
Name
Paracetamol.
Class of drug
Non-steroidal anti-inflammatory drug (NSAID).
Uses
Action
Paracetamol is an NSAID but not a cyclo-oxygenase inhibitor.
Modulates the concentration of prostaglandin intermediates.
Antipyretic.
Poor anti-inflammatory effects.
Indications
Antipyretic.
Controls mild to moderate somatic pain.
Can be administered to patients with gastric ulceration as it produces few gastrointestinal (GI) side-effects.
Administration
Routes of administration
Oral: 500 mg tablets; 125 mg/5 ml, 250 mg/5 ml oral suspension.
Dosage
Basic dose
200-500 mg/kg PO.
1-2 mg/ml of drinking water (use flavored products).
Precautions
Use with care
The main concern with paracetamol is hepatotoxicity.
Interactions
with other drugs
Metoclopramide
Enhances paracetamol absorption thereby enhancing its effects.
Adverse reactions
Other reported reactions
Signs of toxicity include anemia, methemaglobinemia and liver failure.
Anyone else rather :shock: :? about this ?
ETA: claims to be based on the Small Animal Formulary. Tennant Bryn (1999)
Paracetamol
Anna Meredith
Name
Paracetamol.
Class of drug
Non-steroidal anti-inflammatory drug (NSAID).
Uses
Action
Paracetamol is an NSAID but not a cyclo-oxygenase inhibitor.
Modulates the concentration of prostaglandin intermediates.
Antipyretic.
Poor anti-inflammatory effects.
Indications
Antipyretic.
Controls mild to moderate somatic pain.
Can be administered to patients with gastric ulceration as it produces few gastrointestinal (GI) side-effects.
Administration
Routes of administration
Oral: 500 mg tablets; 125 mg/5 ml, 250 mg/5 ml oral suspension.
Dosage
Basic dose
200-500 mg/kg PO.
1-2 mg/ml of drinking water (use flavored products).
Precautions
Use with care
The main concern with paracetamol is hepatotoxicity.
Interactions
with other drugs
Metoclopramide
Enhances paracetamol absorption thereby enhancing its effects.
Adverse reactions
Other reported reactions
Signs of toxicity include anemia, methemaglobinemia and liver failure.
Anyone else rather :shock: :? about this ?
ETA: claims to be based on the Small Animal Formulary. Tennant Bryn (1999)