One of my pair had syphilis when I got them as babies, although I did not know that at the time. It was by posting a picture on here that I found out what the problem was. My normal vet just tried normal prescription treatments which were totally ineffective. After weeks of being subjected to injections I took her to another vet, who used penicillin to treat her. She was quickly cured. As a precaution I had her sister treated at the same time.