keletkezes
Wise Old Thumper
I was wondering what the other ingredients in Metacam (1.5mg/ml for dogs) are:
Erm, I thought xylitol was highly toxic in dogs?!
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Metacam ingredients
- Thread starter keletkezes
- Start date
a reader of books
Warren Veteran
Well, that's strange. Maybe it's only a tiny amount? :?
InspectorMorse
Wise Old Thumper
Probably due to the amount and concentration of Xylitol / ml
If the testing and licensing of all drugs is as vigorous as is claimed I doubt Metacam would have gotten through the process if it was toxic to the species it is aimed to treat.
If the testing and licensing of all drugs is as vigorous as is claimed I doubt Metacam would have gotten through the process if it was toxic to the species it is aimed to treat.
keletkezes
Wise Old Thumper
I expect so (I got this info from the US FDA which is at least as rigorous as UK IMO). There's posts online about not using human formulations for dogs because they (apparently) contain xylitol, so I expect the concentraitions in human are greater. Everywhere definitely says 'even tiny amounts' of xylitol are dangerous/fatal, but that info is aimed at the average Person on the Street. It was actually quite difficult to find the full ingredients in Metacam TBH. I don't know the 'route' of toxicity of xylitol either, if it's something that builds up or something that is 'dosage' fatal, I expect the latter given its use in longterm dog medication!
Just goes to show that information isn't always as 'straightforward' as one might expect :lol:
InspectorMorse
Wise Old Thumper
Very true ! :lol:
InspectorMorse
Wise Old Thumper
Just had this info from my Vet
‘’I spoke with a vet at Boehringer today and as suspected, the level of xylitol is so incredibly low, that even at 1000 times the recommended dose, there is not enough xylitol to cause toxicity issues with the Metacam.
Also, it has had extensive research and trials done, and at 100 times the recommended dose was not toxic over a prolonged period.’’
‘’I spoke with a vet at Boehringer today and as suspected, the level of xylitol is so incredibly low, that even at 1000 times the recommended dose, there is not enough xylitol to cause toxicity issues with the Metacam.
Also, it has had extensive research and trials done, and at 100 times the recommended dose was not toxic over a prolonged period.’’
MimzMum
Wise Old Thumper
Well my faith in Boehringer just went into the toilet. :?
In the U.S. it is gospel that NO amount of xylitol is safe and as Jenna takes this daily I am not happy to have it in there. :evil:
This will require further inquiry on my end, honestly. Before her eye surgery and for a few days afterwards, Jenna was off her metacam and I think her face rubbing and scratching actually waned in that period until her blood concentration amounts of the drug returned to therapeutic levels. If there's any possibility that metacam may be responsible for her current issues, we'll have to explore other forms of NSAID/analgesia for her, forthwith.
She shouldn't be taking it considering her kidney disease anyway, but it's hard to find good pain cover for her now, especially with the lackluster approach her vet takes with her treatment.
Thank you for the info, keletkezes and Jane. xxxx
In the U.S. it is gospel that NO amount of xylitol is safe and as Jenna takes this daily I am not happy to have it in there. :evil:
This will require further inquiry on my end, honestly. Before her eye surgery and for a few days afterwards, Jenna was off her metacam and I think her face rubbing and scratching actually waned in that period until her blood concentration amounts of the drug returned to therapeutic levels. If there's any possibility that metacam may be responsible for her current issues, we'll have to explore other forms of NSAID/analgesia for her, forthwith.
She shouldn't be taking it considering her kidney disease anyway, but it's hard to find good pain cover for her now, especially with the lackluster approach her vet takes with her treatment.Thank you for the info, keletkezes and Jane. xxxx
