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Farewell to my bunny

Happy Hopping

Wise Old Thumper
Well, after reading quite a no. of posting on fellow members' rabbits passed away, I knew eventually
it would be my turn.

My rabbit, a Flemish Giant, passed away on Mon. morning around 9 am, he is just over 4.5 years old,
and myself and my vet (an Exotic Pet specialist specialize in rabbit) and a senior breeder who has
breeding rabbit for 30+ yr. is still wondering what is the cause of death:

On Sat. afternoon, he was hopping so fast in the backyard, I can't catch up w/ him. He did quickly
take one quick bite on some wild weed in the backyard, I can't stop him fast enough (obviously there
shouldn't be any weed in anyone's backyard, but just like everyone's yard, they pops up from time to
time)

On Sat. night around 10 pm, I fed my bunny with the usual--one slice of cantaloupe (the orange round
type) and let him eat as much as he wants.

He used to eat just a little bit, but in the recent weeks, he ate half a slice of a cut piece, in
other words, if you cut a round cantaloupe in 8 - 10 pieces, take one of those, and he ate half of
that one piece, which is a very significant amt. for a rabbit.

However, he has ate the same amt. the night before, and the night before, 4 nights in a row. And
repeatedly the last month or two.

At 1 AM passed Sat. night (i.e. 1 AM on Sun.) he sat on my lap for a much longer time than I expected,
usually he goes away after 5 min. or so.

Because my bunny doesn't eat enough fiber, since he was young, he does has soft poos sometimes.

In the recent mth. starting April after he recover from the sickness of a bacteria infection at the
end of March (his penis touched something on the soil, sickness started around Dec 29,2004), he does
have totally soft poos at around midnight due to the 5 leaf of spinach at 6 pm, and cantaloupe around
10 pm, the soft poos occurred at midnight and I'm used to seeing it, it happened almost every night.

This Sun. at 1 am, surprisingly there is only very little soft poos.

Everything is fine and nights out and bed time around 3 am or so.

On Sun. 8:30 am, he can still walk around. I carried him outside to pee on the garden soil as I
always do it 4 times a day in the summer, but after 1/2 hr. of waiting for him, he won't pee. So I
took him back in the house. He should have pee because it's been 5.5 hr. since his last urinate.

Around 11:30 am or so, something seems to be seriously wrong. I took him outside to pee the 2nd time
that morning, no bunny pee. When I carried him back to 2nd floor, as I put him on the floor like I
always do, he lost his footing. But from the carpet to his feet when I let go, there is only an inch
or so of space gap. Shortly after, his body is soft and laying on the ground.

At first, I gave him 190 cc of SQ fluid (NaCl) because I thought he didn't get enough NaCl on time the
day before, because on Sat., I should have given him 150 cc at 2:30 pm as that's the time he always
gets the NaCl, but for the first time, it's 5 pm instead. The reason was I was planning to use the
juicer to make some carrot juice for him, but I didn't get back until 5 pm, so 150 cc NaCl as usual.

Then came 2 servings of baby food, 6 cc each of potatos organic from Heniz, and 2 cc of anti-biotics,
Enrofloxacin.

From Sun. afternoon till 2 pm, I knew it is quite possible that he is dying. I called my regular vet,
whose an exotic pet specialist, but because it's Sun., noone home, send an email and there is no
reply.

I didn't call the other hospital of the other Exotic Pet specialist (Vet) because I never thought he
will work on any given Sun. Turns out that he was, and left him a mesg. at 3 pm or so. By 3:30 pm,
got an appointment and went to see him.

After 4 X-rays, blood test which didn't came back until Mon 6:30 pm, a no. of other tests, the doctor
said he has a lot of gas build up, my guess is due to the soft fruit cantaloupe. I later on fuond out
the very same slice that he ate, and I also ate the other half, and 1 more slice after that, had
caused me a slight diarrhea as I need to go to the bathroom twice for a bit of soft poo myself. And
he ate that same slice, which is not good.

So the doctor diagnosis at the time was the massive gas build up in his entire body from the x-ray is
causing his body to totally shut down.

He prescribed anti-gas Ovol, Metoclopramide that my rabbit had used in the past yr., Meloxicam, and
Cisapride (think it's a pain killer). Also 45 ml of OXbow Critical Care.

My bunny got all the medication at 6:30 pm, w/ the Meloxicam given to him at the clinic around 5:30
pm. But his body was very weak by then and the vet is concern he won't make thru Sun. night.

My bunny slept besides me the whole night in my bed for the first time in history. By Mon. 2 am he
had occasional rapid breathing, by Mon. 5 am, he had constant rapid breathing, and I knew this is the
end.

I advanced those mediciation w/ the Oxbow to try to gain his strength at 5 am. 36.5 cc. of Critical
Care from Oxbow and by 5:30 am Mon., the Ovol, Cisapride, and Metoclopramide (meloxicam is not needed
as it is a 24 hr. / application drug).

Shockingly he won't swallow the Oxbow at the beginning, he won't or may be can't move his jaw.
Fortunately, 5- 10 min. later, he swallowed the Oxbow and all the medication.

His body got weaker, by 8:45 am or so Mon., there is some uncontrollable pee, and his body started the
uncontrolable shaking movement, so I took him to my bed, comfort him for his final moment, and around
9 am or so, he passed away.


Theory 1:

After his death, I spoke to that 30+ yr. breeder for 2.25 hr., she said:

1) the earlier anti-biotics Enrofloxacin killed the good bateria and the bad bacteria in my rabbit
back from Jan 13 to April 15 or so. The good bacteria is Bactrim Pediatric Susp

2) Although 150 cc of NaCL is given, his intentine still need water, in which the injected NaCl can't
reach, as such, my bunny has a craving for the water content in the soft fruit cantaloupe

3) Hot weather causes my bunny to eat more cantaloupe as well

4) can't explain why he just won't drink the water on the bowl

5) that slice of cantaloupe causes me diarrhea, thus, it is too much for my rabbit

6) shouldn't eat cantaloupe due to moisture contents, and in the wild, no rabbit can reach cantaloupe
tree, or mango tree etc.

Theory 2: By 6:30 pm Mon. the Vet (exotic pet specialist) called for the blood test:

1) something about anemic--my bunny's Jan 13, 2005 test shows Red blood cell count is at the low end
of 31, the new test show 28.

2) High Liver Enzyme indicates either an immediate liver problem caused by bad trauma like injured
from running down the stair or poison or degenerative liver problem caused by cancer.

3) won't make a difference if I see him first thing on Sun. morning

4) cantalopue is a coincidence, wasn't the cantalopue, in all the rabbits he treated w/ gas build up,
they are still all alive today

5) NO chronic kidney damage as per Jan 13, 2005 diagnosis from another Exotic Pet specialist, kidney
is normal w/ a very slight elevated level of ?? from blood test. No kidney stone

6) the non-milky yellow urine is quite normal, the milky yellow urine that my bunny had in the old
days is due to calcium build in, hasty color urine is ok

7) dry fur is not due to lack of NaCl or any kidney failure, rather causes by mal-nutrition, mostly
due to lack of fiber

8 ) My treatment w/ the Na Cl daily, and the hand feeding daily (my bunny is off Hand feeding pellet
since July 6) of pellet extends his life for these months, or else the Liver failure would have kill
him long ago

9) Enrofloxacin is the best, it does NOT kill the good bacteria. 150 cc of NaCL daily injection DOES
gets to the Intestine.

10) the rabbit should drink water even on NaCl injection (he did drink it twice in the past 4 months),
the Not drinking of water is a sign of sickness, primary related to the liver damage

His conclusion is the liver causes the above, not the cantaloupe.

If there is immediate liver damage, he must have fall from the stair or ate the poison on Sun.

-) My rabbit Absolutely didn't fall down the stair or hurt himself, he did eat that single bite of
weed, but can wild weed gets in your garden be poisonous?

I'll double check any moles on the cantalopue, but I don't see how that can be poisonous enough to
kill my bunny.

Which left w/ degenerative liver problem caused by cancer.

It's been a very sad day for me, now I can see how that mother Beth Holloway lost 10 lb. in 10 days
after she lose her daughter in Aruba, I can't eat any meal properly on Sun. & Mon. Lunch and dinner, I
bet I'm already loosing weight.

But before I write my opinion as to which theory is the truth, what do you guys think, which theory is
true? Because the disovery of the truth can help my next rabbit, and perhaps yours as well.
 
hi

:( Sorry you've lost your bunny - but you did comfort him at the end, so take comfort that he didn't die alone, like many rabbits do sadly...

I know he had an unusual diet for a rabbit from your previous posts - too much protein is bad for a rabbit, and nuts are very high in protein and fats - which put a strain on the liver.

Also, NaCl is common table salt - when you say you injected it, how do you mean? It would be a good idea if your bunny didn't drink, to syringe feed water at least once a day - I'm not sure if you did this already?

And I do know that 'bad bacteria' (often caused by too sugary food like fruit) also release toxins, as well as gas, into the system which can cause liver failure eventually - so my guess is this is what happened - rabbit's have a very delicate liver which even things like wood shavings, anaesthetic etc overloads the work of the liver and can cause failure.

Do you have a sample of the weed that he ate? Lots of weeds are not poisonous, but some, like ragwort, and many others that are only in the U.S. may well be - but you need to find out what type of plant it is - again any toxin comes to rest in the liver...

As I lost Pepsi, my bunny last week I know you need to find a reason why this has happened, but at 4 and a half yrs old, it could just be age, or genetics maybe - you did the best you could for him, which is all anyone can do.
 
Sorry for your loss. It is always sad to lose a bunny but must be harder if you are not sure why. He was not ill for long and I'm sure you gave him a great life. I hope you get your answers soon for your peace of mind.


Lynsey
 
I think Elve he was injecting NaCl solution (you can't always inject pure water IV drips are often weak NaCl solutions).

Cisapride (propulsid) is a gut motility drug but works on a different part of the gut to Metoclopramide. Cisapride is usually the best drug to use in stasis cases but it is now banned over here in the UK for human use so we can't get hold of any for our rabbits anymore.

Although melon isn't a natural fruit rabbits would eat I believe many rabbit owners here have fed it to their rabbits with no ill effects however many have also fed banana with no problem yet my rabbit Zeus got stasis from banana.

Enrofloxacin is sold under the trade name Baytril in the UK and is a rabbit safe antibiotic. It doesn't harm the good bacteria in the rabbit's gut so you don't have to worry that was the cause.

From your previous posts I gather he has been sick for a long time and it may be that his internal organs just failed.

Did you get an autopsy done? This may have helped to find out what went wrong.

It is possible that because he wouldn't eat enough fibre his diet became too rich and fatty and contributed to organ failure, but also a heavy bacterial or parasite infection could have caused organ failure and even with an autopsy it may have been difficult to determine a cause of death.

I am very sorry for your loss!

Binky free big boy!

Caz
 
hi

Oh I forgot to say - I thought (correct me if I'm wrong anyone) that big breeds of rabbit tended not to live so long - 7 years is very old for them isn't it? So HH your bunny may just have had age related organ failure :(
 
So sorry to hear of your loss, at least you did everything you possibly could and gave him loads of love and a very happy home.
Take care
Kay
 
Sorry to hear of your loss. Although I am not an expert on bunny illnesses, it sounds to me like he had some sort of liver problem, and that another factor such as the canteloupe or the weed could have proved the trigger for the condition. In other words, I wouldn't have thought that canteloupe would have been the actual cause of death, it may have just triggered a reaction that was already there.

Once again, thinking of you in this difficult time.

AMETHYST
 
I'm so sorry that you lost your bunny, he sounded like quite a special bun. It sounded like you tried everything you could, so don't be hard on yourself. Sending tons of hugs and love. xxxx
Binky free cutie...you always be with us.
 
Re: hi

Hey, thanks everyone for your kind words. I came back from the cremation this morning. The guy at that service said to him out of 1000+ animals that he cremated in 1 yr., only 60 pet owners directly visit his place, most just go thru the vet clinic to get to him indirectly. And in 1 yr., only 2 persons (I'm the 2nd one) sat thru the whole process. But I found a very good co.--he did a sensitive job from the brushing of the bone, to the breaking down of the bone, and the gathering of the ashes, never missed anything bit of ashes.

I then went to talk to someone w/ a MSc in medicial Sc. and this is what he said:

1) if a rabbit drink water, the water goes directly to the stomach, and from the stomatch directly to the small intestines

If it is injected under the skin, it goes to the muscle underneath the skin, the blood vessel then carry the water to all the organs, including the small & large intestines.

Which way is better? I don't know. Perhaps someone else can tell me.

2) that a rabbit not drinking any water even after his bacterial infection in April was fully recovered is an underlying serious problem, it's an indication that something else is wrong, that rabbit on IV per day should still drink some water

3) My bunny has eat 1/2 slice of cantalope for the past month or two, and has eat a bit of cantalope and some watermelon in the past 4.5 yr. (during the summer), as such, that slice of cantalope even it cause me to have a mild diarrhea, can't kill him

It does generates gas, as it is a soft moisture fruit, so I won't be give my next rabbit any soft mositure fruits just in case.

4) The High Liver Enzyme is strong medical evidence that liver failure is the real cause. Blood test doesn't lie. There is no wild weed that we know of in the city that is poisonous, the ones in my yard is the very same as the ones in everyone's yard, that little bite can't be something poisonous. And my bunny positively didn't fall from stairs. So the only thing left is liver damage due to cancer. The anemic red blood cell count also support the above.

5) he had ate cantaloupe, or water melons in the past 4.5 yr., in ea. summer, that slice of cantaloupe can causes gas build up, but it can't cause death. As in the past, I just treated him w/ Metoclopramide.

elve said:
:( Sorry you've lost your bunny - but you did comfort him at the end, so take comfort that he didn't die alone, like many rabbits do sadly...

I know he had an unusual diet for a rabbit from your previous posts - too much protein is bad for a rabbit, and nuts are very high in protein and fats - which put a strain on the liver.

Also, NaCl is common table salt - when you say you injected it, how do you mean? It would be a good idea if your bunny didn't drink, to syringe feed water at least once a day - I'm not sure if you did this already?

Good point. I had 3 rabbits in the past 6.5+ yr. I am relieved to say that w/ small comfort, I was with each one of them in their final moment, so they didn't die alone and they knew that I care about them. It's a peace of mind for me and for them.

Can you or anyone else elaborate on the part where "proteins put a strain on liver"? Even as of April of this yr., I weighed my bunny's weight at the vet clinic, and for a Flemish Giant, his wt. is very good at 14 lb. 8 oz.

That wt. seems to be good for a rabbit of his size. So I assume the protein from the nuts are not excessive.

The NaCl is a SQ fluid injection behind his loose skin just under his neck (loosest part of the body), the reason doctor uses NaCl is because our body, and rabbits, among other animal is composed mostly of NaCl, so they purposedly put NaCl in the water to match our body content. This rabbit won't drink any water, so we need the daily NaCl.

Caz said:
Did you get an autopsy done? This may have helped to find out what went wrong.

It is possible that because he wouldn't eat enough fibre his diet became too rich and fatty and contributed to organ failure, but also a heavy bacterial or parasite infection could have caused organ failure and even with an autopsy it may have been difficult to determine a cause of death.

I didn't get an autopsy because the vet also said even w/ an autopsy, we may not find out. When you said heavy bacterial or parasite infection, you mean something he had months ago or just in that 24 hr time frame? And can you give an example?
 
Re: hi

Happy Hopping said:
Caz said:
Did you get an autopsy done? This may have helped to find out what went wrong.

It is possible that because he wouldn't eat enough fibre his diet became too rich and fatty and contributed to organ failure, but also a heavy bacterial or parasite infection could have caused organ failure and even with an autopsy it may have been difficult to determine a cause of death.

I didn't get an autopsy because the vet also said even w/ an autopsy, we may not find out. When you said heavy bacterial or parasite infection, you mean something he had months ago or just in that 24 hr time frame? And can you give an example?

If you have a long term infection it can lead to blood poisoning in humans which can trigger organ failure. I can't give specific examples. I just wondered as you said your bunny was still experiencing problems urinating whether the bacterial infection he originally had never properly cleared up and it was almost "festering" away in the background putting an extra strain on his organs with the toxins etc that were building up either produced by the bacteria, through the retention of urine or possibly even by the body's own immune response to the infection.

I was speculating really - I have no veterinary qualification.

I think when a beloved pet dies we all ask ourselves questions like why?, could we have prevented it?, what did we do wrong? etc but that is because we care and want to do the best for our animals and not because there may have been anything we could have done to prevent their death.

It is always hard when you have unanswered questions but I think sometimes it is just someone's time to move on to a better place and no matter how hard we try we can't keep them here forever as much as we would like to.

Caz
 
hi

This is a good, brief article about rabbit liver disease (BTW I meant fat is bad for their liver, not protein)
http://www.seattleveterinaryspecialists.com/libr/Rabbit_liver.htm

As you can see from the above, there are a few enzymes which are elavated according to different sicknesses in the rabbit - do you know which enzyme was raised?

Also note 'hepatic lipidosis' near the end of the article - this is what I was referring to when I said rabbit's liver is delicate - fatty liver disease can be caused by a low fibre diet, and by toxins building up in the liver over a period of time from attacks of stasis, bacterial illness etc.

None of which will bring him back, but like you say - you want to protect another rabbit you may have in future from going the same way - Hopefully if and when you feel you want to take on another bunny, you will find one that loves his/her hay, as this will keep them healthy better than any other food.
 
So sorry to hear this sad news. I think you have done your very best and have found out so much as well. I am thinking of you as we all will be because most of us have been through the same.

Binky free and meet all our babies

Rainbowbridge.jpg
 
Re: hi

Caz said:
If you have a long term infection it can lead to blood poisoning in humans which can trigger organ failure. I can't give specific examples. I just wondered as you said your bunny was still experiencing problems urinating whether the bacterial infection he originally had never properly cleared up

I think when a beloved pet dies we all ask ourselves questions like why?, could we have prevented it?, what did we do wrong? etc but that is because we care and want to do the best for our animals and not because there may have been anything we could have done to prevent their death.

After 3 mth. of Enrofloxacin, he is actually baterica free by the end of March, I can tell by the diet and the regular quantity of bunny poos, but another 2 weeks of Enrofloxacin was used because the vet said it takes 3 mth.

By around April 15, the vet done the urine test and confirm bacteria free.

So the urine test confirmed that. But yeah, there is still the unexplained not drinking of water and the "Occasional difficulty in urinating and dropping rabbit poos".

I need to add I was just guessing he is having difficulty due to the tapping of the front legs for a while before he pees. As the behaviour start when he has that bacteria in Dec 29, and continued after his urine showed bacteria free.

And yes, w/ this rabbit and the last 2 that passed away, I always 2nd guess myself if it is something I shouldn't or should have done that can make a difference.
 
Re: hi

elve said:
This is a good, brief article about rabbit liver disease (BTW I meant fat is bad for their liver, not protein)
http://www.seattleveterinaryspecialists.com/libr/Rabbit_liver.htm

As you can see from the above, there are a few enzymes which are elavated according to different sicknesses in the rabbit - do you know which enzyme was raised?
.

That is a very useful link. Thank you very much. As to which enzyme it is, I need to see the report at the clinic next week before we can continue this little chat.


So sorry to hear this sad news. I think you have done your very best and have found out so much as well. I am thinking of you as we all will be because most of us have been through the same.

Marlene, thank you. AS a new measure, I have asked the vet to give me back all medical notes for all 3 rabbits, so I can read more about it and hopefully from the knowledge of those blood tests that it can be useful to prevent similar events of future rabbits under my care.
 
So sorry to hear about you rabbit. Unfortunately i also lost my little maverick last night. I am so shocked. He also had diahorrea, although i didnt notice until i found him, he was still alive but on his way. I was stroking him and he drifted away. I notices the runny poo all round his tail. If i knew i would have taken him to the vet straight away. he was eating and drinking fine previous days. Although yesterday when i went to feed him he did still have some left fro last feed. Not sure if i am going to get a new bun because my mum works now and i have GCSE's to do so we wont realy have enough time to look after it as well as Mav.

RIP bunny, go and play with Maverick, RIP Maverick too.
 
oh no , i,m so sorry to hear this , this is so sad , there are so many that have passed away . inc. my darling baby boy . this is so saddening-its breaking my heart . :( :(
 
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