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Dufophen and lumps on injection sites

saschofield

saschofield

New Kit
Hi,

I have been reading these posts for ages and have finally got around to registering. My brave boy salt (dwarf lop) has had issues from day 1. I got him from a rescue centre with his sister Pepper. Pepper died very suddenly not long after getting her, we don't know why. Salt is affected by the pasturella bacteria. He has frequent ear infections that are very hard to clear up. He has had a number of surgical procedures including having his ear canal opened to allow easier administration of drops and to make the inner ear a dryer environment. He also has to have treatment regular for malocclusion.

I am now very used to medicating him and my wonderful vet is dedicated to him and is very rabbit savvy indeed.

He has recently had his teeth done again and 1 extracted, his gum is sore so vet has had me start dufophen injections. We are rotating the areas jabbed, ie. scruff area and rump etc but he keeps getting lumps come up. They don't seem to bother him, and the last lot were removed and found to be benign. Have any others got any idea why this happens? I am also treating for a ear infection again at the moment too. I have managed to keep him eating through this bout, and he has so far only lost 3 grams.

I love my boy so much but he is a very expensive bunny, nearly £4000 in last 2 years, it is a worry lol

Both my bunnies live indoors with us in a large uncaged area dedicated to them.

Thanks for reading this very long winded post :)

All the best everyone and your bunnies xx
 
saschofield said:
Hi,

I have been reading these posts for ages and have finally got around to registering. My brave boy salt (dwarf lop) has had issues from day 1. I got him from a rescue centre with his sister Pepper. Pepper died very suddenly not long after getting her, we don't know why. Salt is affected by the pasturella bacteria. He has frequent ear infections that are very hard to clear up. He has had a number of surgical procedures including having his ear canal opened to allow easier administration of drops and to make the inner ear a dryer environment. He also has to have treatment regular for malocclusion.

I am now very used to medicating him and my wonderful vet is dedicated to him and is very rabbit savvy indeed.

He has recently had his teeth done again and 1 extracted, his gum is sore so vet has had me start dufophen injections. We are rotating the areas jabbed, ie. scruff area and rump etc but he keeps getting lumps come up. They don't seem to bother him, and the last lot were removed and found to be benign. Have any others got any idea why this happens? I am also treating for a ear infection again at the moment too. I have managed to keep him eating through this bout, and he has so far only lost 3 grams.

I love my boy so much but he is a very expensive bunny, nearly £4000 in last 2 years, it is a worry lol

Both my bunnies live indoors with us in a large uncaged area dedicated to them.

Thanks for reading this very long winded post :)

All the best everyone and your bunnies xx
Click to expand...

Parsley aslo has these lumps - we tested one and then just ignored them. Apparently it is fairly common - I seem to recall it happens in males more for some reason.
 
Lumps at injection sites are often an immflamatory response to the injection however penicillin (which is what is in Duphapen) is supposed to only be injected deep into muscle so if you are injecting into the scruff or subcutaneously elsewhere this could well be causing the problem. Have you tried oral dosing? It's quite unusual to treat a bun with penicillin as a starting point, did your vet try other antibiotics (baytril or septrin) first?
 
RedFraggle said:
Lumps at injection sites are often an immflamatory response to the injection however penicillin (which is what is in Duphapen) is supposed to only be injected deep into muscle so if you are injecting into the scruff or subcutaneously elsewhere this could well be causing the problem. Have you tried oral dosing? It's quite unusual to treat a bun with penicillin as a starting point, did your vet try other antibiotics (baytril or septrin) first?
Click to expand...

You cannot oral dose penicillin in rabbits. In order to lessen the issues they injections are usually placed in alternate muscle areas - left then right etc

It sounds as though the OP has tried the 'usual' abx first - reading between the lines - ear infection can lead to infections elsewhere and usually a rabbit that has got as far as an ear op. will have tried all sorts of abx.
 
RedFraggle said:
Lumps at injection sites are often an immflamatory response to the injection however penicillin (which is what is in Duphapen) is supposed to only be injected deep into muscle so if you are injecting into the scruff or subcutaneously elsewhere this could well be causing the problem. Have you tried oral dosing? It's quite unusual to treat a bun with penicillin as a starting point, did your vet try other antibiotics (baytril or septrin) first?
Click to expand...

PLEASE DO NOT GIVE PENICILLIN ORALLY !! It would be FATAL to do so :cry:

OP, Duphopen can be given subcutaneously, IM injections can be extremely painful.

What size needle are you using and do you use a new needle to inject from the one used to draw up the dose ?

Do you use Trinity Vets in Maidstone by any chance ?
 
Jack's-Jane said:
PLEASE DO NOT GIVE PENICILLIN ORALLY !! It would be FATAL to do so :cry:

OP, Duphopen can be given subcutaneously, IM injections can be extremely painful.

What size needle are you using and do you use a new needle to inject from the one used to draw up the dose ?

Do you use Trinity Vets in Maidstone by any chance ?
Click to expand...

I meant other oral antibiotics orally, not the penicillin, hence why I went straight on to talk about septrin and baytril. Sorry to cause panic! :oops:
 
Jack's-Jane said:
PLEASE DO NOT GIVE PENICILLIN ORALLY !! It would be FATAL to do so :cry:

OP, Duphopen can be given subcutaneously, IM injections can be extremely painful.

What size needle are you using and do you use a new needle to inject from the one used to draw up the dose ?

Do you use Trinity Vets in Maidstone by any chance ?
Click to expand...

Mark at Trinity did the major ear op, he is great...my own vet who knows Mark is also very good, Mark is my port of call when treatment not working so well. He has been on oral Baytril for a while, vet switched to Duphopen last week subcutaneous to try and reduce gum inflammation. He also has ciloxan ear drops 2 times a day and 5kg Dog Metacam 1 time daily. He is 2.81kg at the moment.

I am relieved to hear the lumps not an issue, I am loath to have to have them removed again. The vet draws up all the syringes for me and attaches needles. I just have to point and jab. The needles are 21Gx5/8".

Thanks everyone for the replies I am delighted to have found some support for my poor boy and my poor nerves lol
 
Ugh more lumps

saschofield said:
Hi,

I have been reading these posts for ages and have finally got around to registering. My brave boy salt (dwarf lop) has had issues from day 1. I got him from a rescue centre with his sister Pepper. Pepper died very suddenly not long after getting her, we don't know why. Salt is affected by the pasturella bacteria. He has frequent ear infections that are very hard to clear up. He has had a number of surgical procedures including having his ear canal opened to allow easier administration of drops and to make the inner ear a dryer environment. He also has to have treatment regular for malocclusion.

I am now very used to medicating him and my wonderful vet is dedicated to him and is very rabbit savvy indeed.

He has recently had his teeth done again and 1 extracted, his gum is sore so vet has had me start dufophen injections. We are rotating the areas jabbed, ie. scruff area and rump etc but he keeps getting lumps come up. They don't seem to bother him, and the last lot were removed and found to be benign. Have any others got any idea why this happens? I am also treating for a ear infection again at the moment too. I have managed to keep him eating through this bout, and he has so far only lost 3 grams.

I love my boy so much but he is a very expensive bunny, nearly £4000 in last 2 years, it is a worry lol

Both my bunnies live indoors with us in a large uncaged area dedicated to them.


Thanks for reading this very long winded post :)

All the best everyone and your bunnies xx
Click to expand...

Well he needs a few more injections and vet isn't too concerned about lumps from injection but I am really stressing. He is quite lumpy on shoulder area and rump area, I am a bit squeamish about injecting near these lumps but am running out of unlumpy space.
 
saschofield said:
Well he needs a few more injections and vet isn't too concerned about lumps from injection but I am really stressing. He is quite lumpy on shoulder area and rump area, I am a bit squeamish about injecting near these lumps but am running out of unlumpy space.
Click to expand...

Usually our vets alternate between left and right 'flanks' so to speak. If you are getting a lot of lumps might be worth asking vet whether they think it might be connected to your 'technique'?

We get the vets to do Parsleys (he is now back on it as well!!) as I am rubbish with the penicillin jabs - ok with everything else but just cant get this in!
 
parsnipbun said:
Usually our vets alternate between left and right 'flanks' so to speak. If you are getting a lot of lumps might be worth asking vet whether they think it might be connected to your 'technique'?

We get the vets to do Parsleys (he is now back on it as well!!) as I am rubbish with the penicillin jabs - ok with everything else but just cant get this in!
Click to expand...

Vet watched me do it Friday and said it was fine. I have emailed Mark at Trinity too to ask, I worry so much over Salt. The lumps are also making it difficult to lift his skin to be able to inject. He is having the jab every other day.
 
saschofield said:
Vet watched me do it Friday and said it was fine. I have emailed Mark at Trinity too to ask, I worry so much over Salt. The lumps are also making it difficult to lift his skin to be able to inject. He is having the jab every other day.
Click to expand...

That many lumps does sound extreme - Parsley has his every day and is not covered in lumps - just has maybe 10 or or from over the course of his life.
 
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