I don't have a run, but in the bunnies' room I have vinyl flooring (the kind on a roll, not the plank/tiles type), with some cotton rugs on it. I think that's good for a run, too. It's easy to clean. With the vinyl flooring, though, I prefer the kind that has texture instead of being completely smooth, so the bunnies have more grip. Mine has a fake wood texture and they don't slip on it.