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Leg paralysis, seizures, eye watering

TiminMB

Young Bun
My 8 1/2 year old male rex is experiencing health problems. We are taking him to a vet, but so far nothing has really worked.

For the last couple of years, it appeared that his hind legs were getting stiffer, and he stretched more and more before leaving his cage.

Last December, he began falling over while stretching.

By January, it became clear that his left rear leg was weak, and he was falling over to that side. The vet prescribed nsaids and that has given him some improvement.

He has been treated with antibiotic, baytril twice. First time was for his runny eye. No cloudy discharge, but frequently wet fur beneath the eye. We tried vet prescribed eye drops and baytril, but not improvement. Coincidentally, its the same side as he had the weak leg on.

Now the last couple of months, his left rear leg is getting weaker. He started having seizures, that last a minute or two. Last week he had a seizure that made him cry out loud.

The vet has examined his leg and spine, and cannot find a source of pain.

For the last two weeks he has been on panacur and baytril. We have two more weeks worth of panacur. We are trying this in case it is E. Cuniculi.

His ears and teeth have been examined, and appear normal. He does have some abnormal sensitivity to the base of his ears. When touched, he cranes his head and neck back in a most unusual manner. That started around the same time as he began falling over. Like something is wrong with his inner ears or top of his head near his ears.

He has the odd lump under his skin, but none that have continued to grow. They have been there for a year or two, and the largest is smaller than a pea.

He has had two seizures over the last three days. They last a couple of minutes. He stiffens up, rolls in a ball, and shakes a little, often crying or moaning. After the seizures, he is just fine. Stands right up, eats, seems alert. Like nothing happened.

He still has great quality of life. Has a great appetite, is observant, loves to spend time with me. He doesn't run around like he used to, and can no longer hop up onto couches, etc.

Any suggestions? If he was suffering, I would consider putting him down, but he still has great quality of life. I would like as best to heal him, if possible.

He goes back to the vet in two weeks after finishing the panacur.
 
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Hello, and welcome to the forum:wave: I’m sorry your rabbit is struggling :cry: is your vet experienced with treating rabbits? If not then I would ask if you could be referred to an exotic specialist to get a second opinion.

I’ve not had any experience of this, so I can’t advise further, although I would say I have not heard of a vet prescribing ibruprofren for a rabbit before.

I’m sending lots of vibes for him.
 
The vet is supposed to be good with rabbits. I asked around and she was referred to me by a rabbit rescuer. She used to work at another vet clinic years ago that did surgery on another rabbit of mine and I remember her from there. Its hard to find someone that really knows rabbits.

I am hoping someone might have a similar experience and be able to offer some advice I could take to the vet. She didn't think it was E. cuniculi, but was willing to give it a try to see if it helped.
 
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My 8 1/2 year old male rex is experiencing health problems. We are taking him to a vet, but so far nothing has really worked.

For the last couple of years, it appeared that his hind legs were getting stiffer, and he stretched more and more before leaving his cage.

Last December, he began falling over while stretching.

By January, it became clear that his left rear leg was weak, and he was falling over to that side. The vet prescribed nsaids and that has given him some improvement.

He has been treated with antibiotic, baytril twice. First time was for his runny eye. No cloudy discharge, but frequently wet fur beneath the eye. We tried vet prescribed eye drops and baytril, but not improvement. Coincidentally, its the same side as he had the weak leg on.

Now the last couple of months, his left rear leg is getting weaker. He started having seizures, that last a minute or two. Last week he had a seizure that made him cry out loud.

The vet has examined his leg and spine, and cannot find a source of pain.

For the last two weeks he has been on panacur and baytril. We have two more weeks worth of panacur. We are trying this in case it is E. Cuniculi.

His ears and teeth have been examined, and appear normal. He does have some abnormal sensitivity to the base of his ears. When touched, he cranes his head and neck back in a most unusual manner. That started around the same time as he began falling over. Like something is wrong with his inner ears or top of his head near his ears.

He has the odd lump under his skin, but none that have continued to grow. They have been there for a year or two, and the largest is smaller than a pea.

He has had two seizures over the last three days. They last a couple of minutes. He stiffens up, rolls in a ball, and shakes a little, often crying or moaning. After the seizures, he is just fine. Stands right up, eats, seems alert. Like nothing happened.

He still has great quality of life. Has a great appetite, is observant, loves to spend time with me. He doesn't run around like he used to, and can no longer hop up onto couches, etc.

Any suggestions? If he was suffering, I would consider putting him down, but he still has great quality of life. I would like as best to heal him, if possible.

He goes back to the vet in two weeks after finishing the panacur.

I am sorry to hear about your sick Rabbit.

Has the Vet run any diagnostics-eg Xrays , CT scan, full blood profile

The symptoms you describe sound as though there may be more than one problem going on and without diagnostics it is impossible to establish a definitive diagnosis. A middle ear infection is a real possibility and sometimes this can only be diagnosed by Xrays/CT scan

I would consider seeking a second opinion from a Rabbit Savvy/Specialist Vet

This organisation may help you locate one

https://rabbit.org/vet-listings/

These links provide some information about some of the possible causes of your Rabbit's symptoms. :

Re the slow onset initial 'stiffness'

http://wildpro.twycrosszoo.org/S/00dis/Miscellaneous/Osteoarthritis_rabbits.htm

http://www.meadowlanevets.co.uk/pet-factsheets/Factsheets/Otherpets/24_290501.shtml

Re the subsequent symptoms

https://www.dechra.co.uk/therapy-ar...cs-antifungals/disease-information/e-cuniculi

http://wildpro.twycrosszoo.org/S/00dis/Parasitic/Encephalitozoonosis.htm

http://wildpro.twycrosszoo.org/S/00dis/Bacterial/BacterialOtitisMediaInterna.htm

http://www.veterinarywebinars.com/m...oads/2016/03/Study_Notes_Ear_Nose_Rabbits.pdf

I hope that you are able to obtain some more Veterinary help for your Rabbit x
 
No, no diagnostics run. Perhaps she is trying to save me money by going with the most probable treatments: nsaids, antibiotics and anti encephalitazoan. Or maybe there are other reasons, given his age. But, that isn't working out so well for me. Maybe its my own fault, perhaps I should have asked for more. Maybe she thinks he is at the end of his life, as most people seem to think, and write him off. There are a number of people that just think I should have him put down, but I really enjoy the little guy, and feel that he still gets enjoyment out of life, despite his disabilities. He sure perks up when he sees me, and loves to come out of his cage and spend time with me. It's not as active time as it used to be, not much running around, mostly sitting and mutual grooming. Some times when he comes out, he falls down and gets up quickly, other times he needs help.

I forgot to mention, some times he suffers from urinary incontinence when he falls down. That seems to fit in with the pattern of E Cuniculi.

Thanks for the helpful links.
 
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Vet was kind enough to hand deliver another two weeks worth of baytril. Hopefully one of the strategies (panacur and baytril) pays off.
 
Yes, I am just about due for another follow up. She said there is a medication that may prevent or lessen the seizures, but mentioned that it was sedative in nature. The seizures are very distressing to see, extremely loud screeming and convulsions by my poor bunny. Sometimes he has none for 20 days, and then he may have them two days in a row. They appear so extreme, I'm surprised he survives them. Yet afterwards, he seems just fine.
 
Yes, I am just about due for another follow up. She said there is a medication that may prevent or lessen the seizures, but mentioned that it was sedative in nature. The seizures are very distressing to see, extremely loud screeming and convulsions by my poor bunny. Sometimes he has none for 20 days, and then he may have them two days in a row. They appear so extreme, I'm surprised he survives them. Yet afterwards, he seems just fine.

I think the seizures are probably more distressing for you to witness than they are for your Bunny to experience. The screaming is almost certainly an non conscious event- ie not a direct response to fear/pain, but due to the neurological 'misfiring' in his brain. My Rabbit who had daily seizures in his sleep would sometimes squeal. This would 'wake him up' and he'd hop off and start eating as if nothing had happened.
 
Yes, I am just about due for another follow up. She said there is a medication that may prevent or lessen the seizures, but mentioned that it was sedative in nature. The seizures are very distressing to see, extremely loud screeming and convulsions by my poor bunny. Sometimes he has none for 20 days, and then he may have them two days in a row. They appear so extreme, I'm surprised he survives them. Yet afterwards, he seems just fine.


Yes my rabbit who had seizures was the same - extremely distressing to watch, but recovered from them and behaved as though nothing had happened.

I hope the review goes well and a suitable medication is found.
 
I've had him over 8 years, I love the little guy, and my conscience would not allow me to have him put down just for my convenience. I owe him, he has plenty of credit in the relationship bank.
 
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