Dear All - We are struggling with finding a cure for Fluffy, our Dutch rabbit, and would appreciate any thoughts. He was diagnosed with sarcoptic mange, but nothing seems to be working. He took an Ivermectin shot every two weeks for the last eight weeks, but it has not resolved the problem. His area and bedding were regularly cleaned and changed during treatment, but this has not helped. His companion has not been infected and they have been kept apart for the time being. Fluffy improved slightly after each shot of Ivermectin, but then starts itching again shortly thereafter and the crusts increase. On our visit last week, the veterinarian switched to Selamectin, which he applied topically between his shoulder blades, but that has not had any effect and he has worsened in the interim. The veterinarian suspects that he may have developed resistance to Ivermectin, which is the drug of choice for this condition. We have another appointment in a couple of days and the veterinarian said that he would try another drug related to Ivermectin, to see if that would give a positive result. We're not yet aware of the drug that he will administer during the next visit. We also don’t have many choices for veterinarians in our area. Any thoughts or recommendations would be highly appreciated as we can't stand his suffering and are feeling helpless. Many thanks.