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View Full Version : Millicent has been admitted today/ud p32 Adrenal problem/ we lost her/ pm results



Hugo's There
18-11-2013, 02:55 PM
Today we are hopefully finally going to get to the bottom of Millicent's hormone problem. Our vets have been fantastic :D Our exotics vet has been in touch with the lab who has given her advice on the best way to go about this.

So today millicent has been admitted for a procedure which should not only tell us whether or not she has hormones but also whether they are caused by her ovaries or another issue such as cancer.

It involves a series of blood tests and an injection to stimulate her ovaries if she has any. Not particularly nice for her but a lot less risky than opening up an elderly bunny with an infection in her head.

Hopefully we can get the answers we need and then be able to treat her so she can have the relaxed retirement she deserves. Any vibes for a positive outcome would be appreciated :love:

susie bun
18-11-2013, 02:56 PM
Sending vibes fro the lovely Millicent. :love: xxx

biscandmatt1
18-11-2013, 02:59 PM
sending lots of vibes x

Zoobec
18-11-2013, 03:10 PM
Sending lots of vibes xx

Hugo's There
18-11-2013, 03:35 PM
Thank you :wave:

Also had sienna in today for a dental, chest and skull xrays and a blood test!

Den
18-11-2013, 03:46 PM
Vibes for Millicent & Sienna.

Mackers
18-11-2013, 05:30 PM
Is there an update yet? Hope all went well.

Jojo123
18-11-2013, 05:35 PM
Aww poor bunnies! Hope it went well too

Hugo's There
18-11-2013, 06:09 PM
Is there an update yet? Hope all went well.

No Ive not heard anything :? I keep checking my phone to make sure its not broken :oops:

EBM
18-11-2013, 06:10 PM
sending lots of vibes x

Hugo's There
18-11-2013, 06:25 PM
Thank you



I gave them a ring and Millicent is fine, she coped with it all really well. The results should be back in the next few days.

Sienna's blood results showed chronic inflammation which coupled with her xray results means her tooth roots are giving her a good deal of discomfort. So she will be on daily metacam from now on. She isn't eating yet :(

Mackers
18-11-2013, 06:39 PM
No Ive not heard anything :? I keep checking my phone to make sure its not broken :oops:

I do that too. No news is good news though. Sending our good wishes anyway.

ETA - hadn't read your last post! Glad you've had a positive update but sending eating vibes.

susie bun
18-11-2013, 06:59 PM
Sorry that Sienna is not doing so well. :( Adding vibes for her too. xx

Vegan_Bunny
18-11-2013, 07:11 PM
Sending eating vibes and good news vibes. x

Barn Yard Bunnies
18-11-2013, 07:33 PM
Hope Millicent's results are good news and that Sienna is eating soon.

Talking of Sienna, I just saw her on Hollyoaks. ;)

Hugo's There
18-11-2013, 07:49 PM
Hope Millicent's results are good news and that Sienna is eating soon.

Talking of Sienna, I just saw her on Hollyoaks. ;)

yeah me too. I have had my Sienna for five years, I certainly wouldn't be using that name now :lol:

Barn Yard Bunnies
18-11-2013, 08:01 PM
yeah me too. I have had my Sienna for five years, I certainly wouldn't be using that name now :lol:

:lol: You never know what name will become evil on Hollyoaks. Sienna is a lovely name.

I named my bunny Nancy after Nancy on Hollyoaks. :oops::lol:

Hugo's There
18-11-2013, 08:06 PM
:lol: You never know what name will become evil on Hollyoaks. Sienna is a lovely name.

I named my bunny Nancy after Nancy on Hollyoaks. :oops::lol:

I also had a brendan, again before hollyoaks time. Ive got a Lacey which I think hollyoaks gave me the idea for that name :D

tulsi
18-11-2013, 08:15 PM
Millions of vibes to the beautiful Millicent. Hope Sienna is ok too. xx

MimzMum
19-11-2013, 06:08 AM
Sorry I got to this thread late, Liz. I hope all bunnies are doing well at yours. :) xxxx

Hugo's There
22-11-2013, 02:17 PM
Just a quick update to say no news on Millicent yet. Our vets chased up the lab today but it now turns out results can take up to two weeks so we still have a wait!

tulsi
22-11-2013, 02:35 PM
I do hope you get good news very soon. It seem AGES to wait...

susie bun
22-11-2013, 07:20 PM
Continuing vibes for Millicent. xx

Goth Mummy
22-11-2013, 07:27 PM
That seems like a very long time to wait, but I hope there is good news for all of you.

Hugo's There
29-11-2013, 02:49 PM
So we have had some news about Millicent and I think tbh it is bad news So far I have only had a message left on the phone, I have tried to speak to Juliet but she is incredibly busy today so it might take a couple of days to catch up with her.

Millicents results show that she has no hormones at all in her body. It seems the most likely cause of her behaviour is neurological Given how her behaviour has deteriorated in recent days I completely agree with that. Where we go from here or if there is anywhere to go from here is what we now need to find out.

But unfortunately we now know there is no quick fix and I think we really need to consider her quality of life now and what the future will hold for her

susie bun
29-11-2013, 05:09 PM
I'm so sorry the news and outlook for Millicent is not more optimistic. xx

Hugo's There
29-11-2013, 06:55 PM
Thanks Susan. I am really upset about it as I really thought we could help her and now I feel we can't :cry:

tonibun
29-11-2013, 07:31 PM
Sorry to hear the news about Millicent.

tulsi
29-11-2013, 10:04 PM
So sorry to hear this. She looks like such a little sweetheart ...

MimzMum
29-11-2013, 10:46 PM
Liz, I'm sorry to hear such a dire prognosis, but try to remember you've already helped Millicent by giving her your lovely home to live in. She is in the best possible place and each day in your care is a warm and loving day that she would otherwise not have had. (((((((((Hugs)))))))))))
Bless you, I'm thinking of you all. xxxx

Mrs. Bunnykins
30-11-2013, 05:12 PM
Poor Millicent, what an awful time for you all. :( Sending you a warm and comforting virtual hug on a cold winter's night. xxxx

Sending positive vibes for Millicent too. xxx

Hugo's There
02-12-2013, 03:12 PM
Finally caught up with the exotics vet and all is not lost :)

I sort of misunderstood the previous message left. When she said it is all in her head I assumed it was behavioural but what she meant was that there is definitely no uterine tissue left in her body. We have now caught up with each other for a proper chat and it seems the most likely explanation is an issue with her adrenal glands and pituitary glands. I'm not that knowledgeable about that side of things so need to read up on it. But from my understanding it is not related to her infection and is not caused by any other infection or cancer so that is good. Apparently it is something which is much more common in ferrets. We are putting her on to high level metacam from today to see if that helps any of her behaviour and then she is having a hormone implant fitted on Friday. Then it is just a case of waiting to see if it helps her. The vet agrees that it is likely that Millicent is unhappy at the moment and would potentially benefit from bunny company, something that really isnt possible right now :( But at least there may be something we can do, so not feeling quite as helpless as I did.

I am really disappointed with the previous rabbit vet for not wanting to investigate this despite us raising it as a concern at every consult and being told to leave her be on her own :cry: This issues is seriously affecting her quality of life. We wont be travelling back there again

Jack's-Jane
02-12-2013, 04:01 PM
Brian has adrenal neoplasia/hyperplasia

Molly Varga has written a paper on it which Marie sent me. John Chitty has written something too which Marie also emailed to me.It is in the Journal of Exotic Pet Medicine from January 2006.

The Suprelorin implant was recommended

Hugo's There
02-12-2013, 04:07 PM
Unless I am mistaken I think most of the research has been done about male rabbits rather than female rabbits?

ETA Is Brian's adrenal cancerous? I seem to remember it is. I specifically asked if there was cancer and she said no it was some kind of hypersensitivity :?

Personally I think this is the very best outcome for her. If it was just behavioural then there was little we could do to change things. If there was an minute pieces of ovarian tissue left it would ahve been a huge risk putting her under given her age and other health problems. At least with this we have a chance of helping her with something that isn't invasive :D

susie bun
02-12-2013, 08:47 PM
I'm pleased to see it is looking more like something can be done to help Millicent. Well done for persevering. :thumb: She is a lovely bun. x

Hugo's There
02-12-2013, 08:57 PM
Thanks Susan x

Barn Yard Bunnies
02-12-2013, 09:48 PM
So glad its not bad news. Hope with treatment Millicent does well.

Hugo's There
02-12-2013, 10:06 PM
So glad its not bad news. Hope with treatment Millicent does well.

Thanks Amanda :wave: It may still be bad news but at least there is a chance to help now. Its horrible feeling helpless :(

Speaking to a couple of other people on fb who have had a rabbit with similar problems, one was treated by FHB and she believes most adrenal tumours are non cancerous :) Another I think was treated by Molly Varga but unfortunately the implant didn't help them :( Again both rabbits were male :?

Barn Yard Bunnies
02-12-2013, 10:11 PM
Thanks Amanda :wave: It may still be bad news but at least there is a chance to help now. Its horrible feeling helpless :(

Speaking to a couple of other people on fb who have had a rabbit with similar problems, one was treated by FHB and she believes most adrenal tumours are non cancerous :) Another I think was treated by Molly Varga but unfortunately the implant didn't help them :( Again both rabbits were male :?

I hope it does work. Thank goodness for FHB, I have found what I have read about her research in some areas very interesting, but mainly on dental issues.

At least Millicent is ok for now.

Hugo's There
02-12-2013, 10:37 PM
Thank you. I really hope we can make her a bit happier. I dont like her eyes they are sort of flat and dead, and she has become aggeessive. It would be goid to be able to cuddle her again :)

Barn Yard Bunnies
02-12-2013, 11:50 PM
Thank you. I really hope we can make her a bit happier. I dont like her eyes they are sort of flat and dead, and she has become aggeessive. It would be goid to be able to cuddle her again :)

Hope its not too long. Its hard when you know they are not well and even harder when you don't know exactly what you are dealing with.

MimzMum
02-12-2013, 11:59 PM
Hormones are such a burr in the saddle, can't live with 'em, can't live without 'em! :( Although, until going through the change myself I had no idea how happy I would be without! :shock:
I am surprised to find that this has such an influence on rabbit mood and health. You would think it would be the opposite.

I wonder if treatments in this field in female rabbits are simply not done because of things like uterine cancers and such? Is it hormones that play the biggest role in causing cancer in unspayed does? It does in people (at least in my case) my BC was hormone driven. It was just a matter of eliminating them to put me in remission. Of course, there are medications that then need to be used to stop the hormones coming from the adrenals too, so apparently they are capable of taking up the slack, but I guess poor Millicent doesn't have any, poor thing. :(
From what you describe with the pituitary involvement it almost sounds like a kind of Addison's/Cushing's Disease. But I'm rambling.... :roll:

I just really wanted to send vibes. Poor wee bub, I hope that there can be an implant found to help her. She sounds like such a sweetie. Thinking of you. xxxx

Hugo's There
03-12-2013, 08:26 AM
Thank you for posting. I need to wait until my brain is having a good day and then read up on pituitary and adrenal glands.

I guess it is also a little more difficult to work out what is what with her because she already has infection in her head which has spread to the bone. We are hoping that is presently under control but we really cant say for certain what is going on in there

MimzMum
03-12-2013, 08:29 AM
Aw poor thing, :( sending more vibes for the best possible outcome for Millicent for all her issues. xxxx

tulsi
03-12-2013, 08:10 PM
Bless her. She is one of the rabbits on here that I have grown very fond of. I do hope she will be able to have a friend to cuddle up to x

Hugo's There
04-12-2013, 02:34 PM
Bless her. She is one of the rabbits on here that I have grown very fond of. I do hope she will be able to have a friend to cuddle up to x

Thank you. That is really kind xx

Hugo's There
04-12-2013, 02:42 PM
We have been to the vets twice for Millicent today as she is having real trouble urinating now :(

Managed to get a sample and had the results back. They are odd as protein is very high but concentration is normal. So she will be blood tested on Friday when she goes in for her implant. Especially as she has just been started on high levels of metacam.

Also Juliet is wanting to refer her to a specialist for a scan of her adrenal glands as this is the only way to see if there is a tumour. A normal ultra sound isnt sensitive enough to pick them up. Millicent travels well so that isnt a problem but Steve only has two days off between now and Christmas so when we can do it I dong know.

We will discuss it again on Friday when we have her blood results. Until then I am closely monitoring her urine output. But over thd last few days she has only wee'd once every 24-36 hours :(

tulsi
04-12-2013, 09:28 PM
Aw bless her. I am sorry to hear this.

Hugo's There
05-12-2013, 09:41 AM
Aw bless her. I am sorry to hear this.

Thank you for your reply x

Millicents cage is dry again this morning which means the last time she urinated was 6.30 yesterday evening :(

Hugo's There
06-12-2013, 10:13 AM
More bad news at vet today.

No implant as vet very worried about her urinating. Bloods taken and sent to lab so wont get results until next week. Also pus has returned to her ear :(

Also the vet is worried about the mass in Geoffs abdomen so he is being xrayed again next week. But thankfully he has now come back negative for coccidiosis

MimzMum
06-12-2013, 11:28 AM
Gosh Liz, I'm so sorry. :( Sending vibes for Millicent and Geoff that all will come round right again for them. xxxx

Jaysmonkey
06-12-2013, 11:41 AM
I'm sorry Liz :( what terrible news.

Hoping for a miracle x

Hugo's There
06-12-2013, 11:55 AM
Thank you both x

Juliet has contacted a number of specialists about Millicents hormone results and urine sample but no replies yet :(

tulsi
06-12-2013, 12:20 PM
Thank you both x

Juliet has contacted a number of specialists about Millicents hormone results and urine sample but no replies yet :(

I really hope that you get some good news. Poor love x

susie bun
06-12-2013, 12:36 PM
Adding my vibes for Millicent and Geoff. xx

Vegan_Bunny
06-12-2013, 12:45 PM
Sending more vibes. I hope she can fight off this horrible infection and get her adrenal gland problem sorted out. Also sending vibes for Geoff. It must be very stressful for you. *Hugs*

Hugo's There
10-12-2013, 02:21 PM
We have more test results for Millicent and it gets stranger!

Not spoken to Juliet yet as she isnt in until Friday so not sure what it all means.

Her kidney function is fine so not sure why she is suddenly weeing so infrequently. But she has come back as having high testosterone levels!I always said she behaved more like a male than an unneutered female.

For now Millicent is booked in to see Juliet friday morning for the implant and ear check so I will have more info then.....

Jack's-Jane
10-12-2013, 02:28 PM
We have more test results for Millicent and it gets stranger!

Not spoken to Juliet yet as she isnt in until Friday so not sure what it all means.

Her kidney function is fine so not sure why she is suddenly weeing so infrequently. But she has come back as having high testosterone levels!I always said she behaved more like a male than an unneutered female.

For now Millicent is booked in to see Juliet friday morning for the implant and ear check so I will have more info then.....

Adrenal tumours can secrete testosterone

http://www.memorialregional.com/services/endocrine/hormonally-active-adrenal-tumors.cfm

Hugo's There
10-12-2013, 02:36 PM
This is what the vet said. But the only way to get a definite diagnosis is to take her to a specialist for an ultrasound scan. We dont know which vet has the right scanner until we speak to Juliet friday x

tulsi
10-12-2013, 03:40 PM
Lots of tender and loving vibes to beautiful little Millicent xxxx:love:xxxx

susie bun
10-12-2013, 03:52 PM
Continuing vibes for Millicent. xx

Hugo's There
12-12-2013, 11:15 AM
We lost Millicent this morning. Totally gutted :(

Fellie
12-12-2013, 11:33 AM
Oh no - such sad news! Very very sorry.:cry:

Jaysmonkey
12-12-2013, 11:35 AM
Oh no :cry:

I'm so incredibly sorry.

Binky free sweet Millicent xx :(

parsnipbun
12-12-2013, 12:05 PM
I am so very sorry - you and she tried so very hard.

susie bun
12-12-2013, 12:45 PM
Oh no, I'm so very sorry. :( You tried so hard for her.

Binky free Millicent. xxx

Mackers
12-12-2013, 01:04 PM
Oh Liz, I'm so very sorry :cry:.

Jack's-Jane
12-12-2013, 01:05 PM
Goodness what a shock :shock: :cry:

I am sorry :cry:

Sam and Truffs
12-12-2013, 01:30 PM
I'm so sorry. You did your absolute best for her.

RavenMoon
12-12-2013, 01:32 PM
Oh I'm so sorry :( She put up quite the fight bless her xxx

Hugo's There
12-12-2013, 02:22 PM
Goodness what a shock :shock: :cry:

I am sorry :cry:

Yes and no. I was expecting it to happen but not quite so soon. I just knew the infection had spread to her brain despite the rabbit "specialist" giving her the all clear. When the pus returned last week I was really hoping we could still give her more time.

She developed a horizontal nystagmus late last night. By 3am her head was shaking. Got an appointment first thing with our vet but she took a massive turn for the worst while we got ready. It was horrible :(

It wouldnt have been fair to expect her to fight any longer :(

Mrs. Bunnykins
12-12-2013, 02:39 PM
Liz, I'm so sorry.:cry::cry:

ripminnie
12-12-2013, 02:52 PM
I'm so sorry to see this :cry: xxx

Jenova
12-12-2013, 02:58 PM
So sorry. :(

KarenM
12-12-2013, 04:22 PM
Poor Millicent, I'm so sorry. :(:(

tonibun
12-12-2013, 05:16 PM
Sorry to hear about Millicent. Very sad.

mushlett
12-12-2013, 05:41 PM
I am so sorry xx

tulsi
12-12-2013, 06:00 PM
Awww Millie xxx:love:xxx I am so sorry to hear this xxx:love:xxx

RIP Millicent.

JemimaH
12-12-2013, 06:03 PM
Oh no :( You did everything you could.

Sleep tight Millicent xx

Hugo's There
12-12-2013, 08:18 PM
Thank you for your replies they are appreciated.

Although we know it was her ear infection spreading that killed Millicent we asked for a PM to see what else was going on. It confirmed that she did have a tumour in one adrenal gland. We opted not to send it away to check for cancer as just knowing it was there is enough.

I cant tell you how disappointed I am in the vets that specialises in rabbits and I cant repeat what steve thinks! Every appointment we brought up her hormones but they were never interested and refused to take it further. That along with the low level of pain relief they gave her its safe to say we wont use them again :(

silverrabbit
12-12-2013, 08:24 PM
I'm so sorry :cry:

Zoobec
12-12-2013, 09:09 PM
I'm so sorry you lost her :cry: sending hugs xx

MimzMum
12-12-2013, 09:13 PM
Oh no, Liz I've just seen this :cry: I'm so very sorry.
Just gutted...I have no words, even when we prepare ourselves for the worst it's always shocking to have it happen when you're trying so hard to prevent it. :(
((((((((Huge hugs)))))))) for you and Steve. Sweet dreams Millicent, you beauty. xxxx

Den
12-12-2013, 09:17 PM
I'm so sorry.

Binky Free Millicent.

tulsi
12-12-2013, 09:29 PM
Shocking that a rabbit expert vet would not investigate hormones ... and LOW levels of pain relief. I wanted to punch them when you said that. Poor Millicent x

BerryJane
12-12-2013, 11:25 PM
so sorry that you lost her and that you and her were treated so poorly. Take care xx

Captain Helen
13-12-2013, 12:29 AM
I'm so sorry :cry: Binky free Millicent xx

Santa
13-12-2013, 09:10 AM
:( So sorry to hear this Liz, and so sorry that your experience of a rabbit specialist wasn't as you had hoped or perhaps indeed had paid for! I hope that you can get some comfort from knowing that the issue was with her adrenal glands and that maybe this knowledge and experience with Millicent may prove valuable to support other bunnies in the future xxx