I think at the end of the day you just have to be firm and keep picking him up to get him used to it. One of my bunnies was so terribly traumatised when I took him on and even hated being looked at let alone picked up. But now he actually asks for cuddles. I don't really agree with not picking them up, because what if he had an accident or was ill, and you had to pick him up and do things with him, giving him meds, maybe having to wash him or change dressings etc, then isn't really the time to start getting him used to being picked up, and he could potentially do himself more damage if injured by struggling so much. It's the same with travelling. I take my bunnies for a half hr. drive every week, and now they start of madly excited, periscoping trying to look out of the windows on the way out and sleeping like babies and sometimes snoring on the way back, and it is now like a fun different thing for them to do, which also means that when they have to go to the vets, they haven't got all the additional stress of not being used to travelling.
I've even taken Bodger and Paddington in trolleys round supermarkets. In Asda the Manager came up to me and said I couldn't have a bunny in the trolley, but as I rightly pointed out, it says 'NO DOGS' not 'NO RABBITS', and so he did have to let me continue doing my shopping. Very embarrassing though when Paddington made a lunge for the broccoli. Good job he had a harness on, or he would have landed right in the middle of it, and I guess we could have been thrown out then :lol::lol: