When our Wilson started with headtilt to start off with he was just on baytril, panacur & metacam - this was when his head was only slightly tilted. He then got progressively worse & his tilt changed sides - it was so bad his down eye was almost horizontal to the floor. We then changed him to steroid injections, depocillin injections & panacur - again sadly these did nothing for him.
He was having severe rolling episodes & we had to confine him to a padded cage for around 6 weeks approx 3ft x 1 1/2 feet. Eventually after bunny mad lisa on RU suggested it - we talked to our vet about Zithromax - Lisa had, had great results with it her for her headtilt bunny - we felt we had no options left but to try it.
We switched him onto Zithromax & also started him on stemetil (human anti sickness drug) - continued with his panacur & I *think* his steroid injections. After just over a week of this treatment he was well enough to come out of his cage & go back with his partner Alice. We'd kept them in the same room at all times, but had to confine Wilson to a cage so he didn't hurt himself or Alice.
I have been told & read that the best way to deal with headtilt is to treat with as much strength of medication as possible - I think basically to try to beat the infection before it gets worse.
We never got to the bottom of what caused Wilson's headtilt & even now his head is still almost at 90 degrees to the floor, but he manages absolutely fine & has learnt to live with his head like this. Touchwood he no longer rolls & has managed to adjust to life with a wonky head over two years since first becoming poorly.
Wilson's original thread is below - warning though it is very long, as we had another 2 sick buns at the time
http://forums.rabbitrehome.org.uk/sh...lsons+headtilt
I wouldn't leave Victor alone over night even if he's eating - if he starts rolling even if he is confined to a cage, it can be distressing for them & they need re-assurance or even help to right themselves. Wilson was so stressed when he first become ill & started rolling - he needed re-assurance & comforting.
I don't know what vets you use etc or what their options are for keeping him overnight, but imo he needs someone there to ensure he is ok & not be left on his own.