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I've asked this before and while it seems logical that the bun would develop immunity and thus make it less likely, there was someone on the forum whose bun had myxi twice
My vet has always insisted on vaccinating Damson again even though he has had it. She didn't do it for the first year but then said we ought tp start again. I believe there are slightly different strains.
Lola had suspected Myxi last year (swellings, weight loss etc) but fully recovered and still has all her jabs. Was just wondering if she could still catch it!