It's not actually known whether or not Lactucin does become Lactucarium (an Opiate) once ingested by rabbits, or people for that matter, but there have been many reports of rabbits becoming 'soporific' following feeding of large amounts of lettuce. As Lactucin is converted to Lactucarium you can't say it is 'fiction'. It is 'fact' that is exists - what is not known is whether or not the compound Lactucarium will result following ingestion - this doesn't mean it's fiction - simply that it is unknown! I agree that It's always better to avoid the unknown in plants where rabbit health is concerned.