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highest dosage of panacur for a 4kg bun

B

bunnyrun

Mama Doe
does anyone know what the highest dosage of panacur should be for a 4kg french lop,

to cut a long story short my french lop has severe head tilt and is now flipping, today its worse than ever:cry::cry::cry:

got the vets at 2.20

i need to be sure she,s having the right quantity before i make a heartbreaking decision:cry::cry:
 
0.8ml of the 10% oral solution (0.2ml per kg).
Is she having Stemetil (or similar) and Metacam or Steroids too?
Has an ear infection been ruled out?
 
The dose is 20mg/kg

So the Bun would need 80mg

Is she on anti-inflammatories? These are an essential part of the treatment of EC

The clinical signs are due to both direct damage - where the parasite deprives the cell it lives in of essential nutrients by removing them for its own use, and indirect where the foreign proteins of the parasite stimulate the immune system to attack and destroy the infected cell, particularly when the spore causes the host cell to break open and release all the new spores and damaged cell contents. If the immune system mounts a very aggressive attack (dependent on infected cell levels, foreign protein reactivity, immune system function, concurrent disease, white blood cell type proportions and many other factors) then the protective response becomes damaging as surrounding normal cells are damaged by the reactive molecules released in response to an infected/damaged cell. These molecules cause further cell damage, further inflammation and delay healing so can actually prolong and exacerbate the disease process.
This is why metacam and other anti-inflammatories are really important in stopping progression. They don't treat the parasite but control the body's response to it. Steroids would act in a similar way but have a more widespread suppressive effect on the immune system and with an infectious disease it is better to try and keep the majority of immune function intact to stop the infectious organism being allowed to multiply unchecked.
Does that make sense (and was that even an answer to the question asked?), it's the kind of simplified explanation but there are still a massive amount of unknowns in the e.cuniculi disease process (am trying to get several research projects off the ground at the moment so hopefully more answers will be provided over the next few years).

Marie Kubiak
ECAMS Resident in Avian and Exotic Medicine
Great Western Exotic Vets
Great Western Referrals
Swindon
 
with the ongoing problems i have with my vets ive spoken to horsham vets who have rabbit specialists, they are happy to see her, my vets "dont see it neccessary" for her to be on pain relief as apparently she isnt in pain:cry: but i need her seen at my vets to see if we can stop the flipping to a degree so its safe and comfortable for the hours journey up there
 
bunnyrun said:
with the ongoing problems i have with my vets ive spoken to horsham vets who have rabbit specialists, they are happy to see her, my vets "dont see it neccessary" for her to be on pain relief as apparently she isnt in pain:cry: but i need her seen at my vets to see if we can stop the flipping to a degree so its safe and comfortable for the hours journey up there
Click to expand...

Is it Seers Croft in Horsham you are going too? We used them for my childhood bunnies when I lived in W Sussex.

The Metacam isn't used for pain, it's used for it's anti-inflammatory properties, as explained in Jane's post. Panacur will only stop the progression of the EC it won't undo the symptoms alone.
 
yes its seerscroft, i phoned them and was very impressed with the girl i spoke to, they did say tho that if she was really that bad they would recommend pts which is what my vets have suggested
 
bunnyrun said:
yes its seerscroft, i phoned them and was very impressed with the girl i spoke to, they did say tho that if she was really that bad they would recommend pts which is what my vets have suggested
Click to expand...

I would try to get your Bun onto some Metacam before making any big decisions. Bun may well improve markedly once on the correct treatment.

You could print off Marie Kubiak's advice in my previous post and take it to show the Vet.
 
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